Justicia gendarussa plant was collected from kanjikode hills, kerala. Justidrusamides ad, new 2aminobenzyl alcohol derivatives. It is believed to be native to china and is distributed widely across india, sri lanka, and malaysia. Although there is yet no cure for hiv, the chemical compound, called patentiflorin a derived from a medicinal plant found in east asia. Biomass production and antibacterial activity of justicia gendarussa. Effect of nitrogen nutrition of stock plants of justicia. Corrosion inhibition effect of justicia gendarussa extract jgpe on mild steel in 1 m hcl medium has been investigated by weight loss and electrochemical techniques. Prick out the seedlings into individual pots when large. However, it has never been studied for the purpose of corrosion inhibition. Arumagaswamy, plant taxonomist of kongunadu college of arts and science, coimbatore, india. Justicia gendarussa is cultivated, and naturalized in forest, forest borders and on river banks in java, up to 1500 m altitude. Potent inhibitor of drugresistant hiv1 strains identified. All natural no artificial ingredients gmo free carefully manufactured by mars herbal, llc. Justicia gendarussa methanolic leaf extracts from five different locations in the southern region of peninsular malaysia and two flavonoids, kaempferol and naringenin.
Present investigation deals with the phytochemical and antioxidant studies of justicia gendarussa burm. Justicia gendarussa, a medicinal plant collected in vietnam, was identified as a potent antihiv1 active lead from the evaluation of over 4500 plant extracts. Justicia gendarussa or known as gendarussa is a member of acanthaceae family. General information justicia gendarussa is a muchbranched, erect shrub growing from 70 150cm tall. Since 1987, however the year in which azt azidothymidine was approved by the u. Management of leaf rust disease of medicinal plant. Justicia gendarussa, belongs to family acanthaceae, and generally found in coastal region of india. Easy, grows to 36 in the sun or shade, likes moist soil. Its actual native distribution is not certain because it is often not clear whether particular collections are native. The active plant is determined as justicia gendarussa acanthaceae, a medicinal plant that has been used for the treatment of injury, arthritis and rheumatism in asia including china. Introduction biological screening is necessary to provide a scientific basis for validating the.
Justicia gendarussa, gendarussa vulgaris, daun rusa. It combines 4coumaroylcoa with three c2 units from malonylcoa to produce naringenin. Vasculoprotective effects of centella asiatica, justicia gendarussa and imperata cylindrica decoction via the noxsrosnf. Biosynthesis of tio 2 nanoparticles using justicia. The aim of the present investigation was to evaluate the hepatoprotective effect of the leaf methanol extract of j. Preminelary experiment showed that ethanolic extract ofgandarusa leaves justicia gendarussa burm. Jg, family acanthaceae, known as gandarusa, is found in indonesia and also in several other countries in asia such as sri lanka, india, and malaysia.
For more multimedia, look at justicia gendarussa on wikimedia commons. Antiarthritic potential of the plant justicia gendarussa. Justicia gendarussa methanolic leaf extracts from five different locations in the southern region of peninsular malaysia and two flavonoids, kaempferol and naringenin, were tested for cytotoxic activity. In the philippines, it often grows along streams in primary and secondary forest. Pdf phytochemical and pharmacological profile of justicia.
This is the first report of a 2,3dihydroxy21hydroxyethyl butanoic acid derivative in nature. Justicia gendarussa variegata variegated water willow, tuhod manok an asian species, popular in the tropics especially the philippines. It has been traditionally used in many parts of the world to help with injuries and ailments, but one tribe in the papua province of indonesia found that drinking a tea made by soaking the plants leaves in water could cause temporary infertility. Quality of gandarusa herbal material and extract are not available in indonesian herbal pharmacopeae fhi yet. Ecofriendly biosynthesis of polycrystalline titanium dioxide tio2 nanoparticles nps was synthesised using justicia gendarussa j. Evaluation of the compound against both the m and ttropic. Detection of naringenin and kaempferol in justicia. Metabolite profiles in various plant organs of justicia. Corrosion inhibition by justicia gendarussa plant extract in. The dried leaves were ground into small particles and approximately 50 g of small particles was soaked into. It has been traditionally used in many parts of the world to help with injuries and ailments, but one tribe in the.
B pathway in spontaneously hypertensive rats author links open overlay panel erna sulistyowati a b 1 renlong jan c d 1 shufen liou e yingfu chen a f g binnan wu a h jonghau hsu a j k jwulai yeh a h i l. Download hires image download to mspowerpoint cite this. Justicia species is found to contain alkaloids, lignans, naturally occurring phenolic dimmers, plant oils, flavonoids and osubstituted aromatic amines. Tuhodmanok kapanitulot justicia gendarussa gandarusa. Calyxbelongs to family acanthaceae is commonly known as nilinirgundi. A great number of screening programs are going on worldwide for new plant based bioactive molecules. Justicia gendarussa in the germplasm resources information network grin, u. Tuhodmanok is a shared common name by 1 dayang, cyathula prostrata, and 2 gandarusa, justicia gendarussa. It is commonly found throughout the greater part of india and andaman islands.
Media in category justicia gendarussa the following 32 files are in this category, out of 32 total. In this study the structural elucidation of the bioactive component present in this plant that triggers antiinflammatory effect was studied and its molecular mechanism was elucidated via tlrnf. Evaluation of antiangiogenic effect of the leaves of justicia gendarussa burm. Kaempferol and naringenin were two flavonoids detected in leaf extracts using gas chromatographyflame ionization detection gcfid. The antiarthritic potential of the alcoholic extract of the plant justicia gendarussa was evaluated using the freunds adjuvantinduced and collageninduced arthritic. Pdf biosynthesis of tio2 nanoparticles using justicia. Gandarusa leaves were collected from tawangmangu, solo, and padang region. Phytochemicals of gandarusa justicia gendarussa and its. Acanthaceae is a shadeloving, quickgrowing, evergreen plant mostly found in moist areas. Introduction biological screening is necessary to provide a scientific basis for validating the traditional utilization of medicinal plants. Summarythe effect of the nitrogen nutrition of stock plants of justicia gendarussa l. While some claim the shrub originally came from india, evidence exists that suggests that the shrub calls most of asia home, including the island of papua. Flavonoid content and alkaloid content introduction justicia gendarussa of leaves. Bioassayguided separation of the extracts of the stems and roots of this plant led to the isolation of an antihiv arylnaphthalene lignan anl glycoside, patentiflorin a 1.
Justicia gendarussa is a medicinal herb enriched with phytochemicals having curative effects against inflammatory diseases. Justicia gandarusa extract now shipping worldwide pure. Detection of naringenin and kaempferol in justicia gendarussa. Biosynthesis of tio2 nanoparticles using justicia gendarussa leaves for photocatalytic and toxicity studies. Justicia gendarussa, commonly known as willowleaved justicia marathi. Therefore, there is a need to establish quality from them. Vasculoprotective effects of centella asiatica, justicia. Evaluation of antiangiogenic effect of the leaves of. Two new antihiv arylnaphthalide lignan glycosides were isolated from the stems and barks of justicia gendarussa. Biochemical studies highlighted that in leaf tissue, quantities of soluble carbohydrate, amino acid and ascorbic acid are of 307 mgg, 34.
Justicia gendarussa significantly slows down the progression of. Justiprocumin b 2 displayed potent inhibition activity against a broad spectrum of hiv1 strains including the nrti and nnrti resistant strains. Justicia gendarussa variegata vintage green farms with. Corrosion inhibition by justicia gendarussa plant extract. Biosynthesis of tio2 nanoparticles using justicia gendarussa.
Extracted rna, treated with rq1 rnasefree dnasekit and cdna synthesis in order to prepare the rich template of dna for pcr by using mmlv reverse transcriptase kit. Isolation, identification and characterization of apigenin. Dec 11, 2014 cytotoxic activities against breast cancer cells of local justicia gendarussa crude extracts zahidah ayob, 1 siti pauliena mohd bohari, 1, azman abd samad, 1 and shajarahtunnur jamil 2 1 department of biotechnology and medical engineering, faculty of biosciences and medical engineering, universiti teknologi malaysia utm, 810 johor. Metabolite profiles of plant organs and their in vitro cultures of justicia gendarussa have been studied by using ultra performance liquid chromatographyquadrupole timeofflightmass spectrometry uplc. High quality cdna synthesis and amplification of chalcone.
The total rna was isolated from the mature leaves of justicia gendarussa burm. Cytotoxic activities against breast cancer cells of local. Antihiv diphyllin glycosides from justicia gendarussa. Pdf biomass production and antibacterial activity of. Justidrusamides ad 14, four new alkaloids containing 2aminobenzyl alcohol, succinic acid, and 2,3dihydroxy21hydroxyethyl butanoic acid skeletons have been isolated from leaves of justicia gendarussa, and their structures were elucidated using 2d nmr data and chemical means. Acanthaceae daun rusa, gandarusa, water willow origin. Gandarusa, a naturally derived extract, comes from native indonesian shrub, justicia gendarussa. Antiarthritic potential of the plant justicia gendarussa burm f. Justicia gendarussa, or the willowleaved justicia, is a shrub with dubious origins. Prick out the seedlings into individual pots when large enough to handle and grow on in the greenhouse for at least the first winter. Isolation and characterization of phytol from justicia. The dried leaves are used to repel insects from clothing. Hepatoprotective and antioxidant activities of justicia. Justidrusamides ad 14, four new alkaloids containing 2aminobenzyl alcohol, succinic acid, and 2,3dihydroxy21hydroxyethyl butanoic acid skeletons have been isolated from.
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